10 Random Questions
A 70-kg 22-year-old patient with head trauma and multiple fractures of the long bones is scheduled for fixation of bilateral femoral fractures. Preoperative laboratory studies show a serum sodium concentration of 150 mEq/L, a serum potassium concentration of 3.1 mEq/L, and a urine output greater than 500 ml/hr. Which of the following agents will decrease urine output?
(A) 3% Saline solution
(B) 5% Dextrose solution
(C) Glucagon
(D) Hydrocortisone
(E) Vasopressin
Reveal Answer
ADVANCED
Respiratory & Critical Care
Maternal hyperventilation produces
(A) decreased maternal arterial pH
(B) increased fetal cerebral blood flow
(C) increased fetal arterial pH
(D) decreased maternal uterine artery flow
(E) increased fetal arterial P02
Reveal Answer
With long-term administration, which of the following drugs produces the most prolonged sedative effect of diazepam?
(A) Cimetidine
(B) Famotidine
(C) Metoclopramide
(D) Ranitidine
(E) Warfarin
Reveal Answer
Compared with thiopental, methohexital is characterized by
(A) better absorption after rectal administration
(B) greater protein binding
(C) greater hepatic clearance
(D) larger volume of distribution
(E) more complete biotransformation
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
Which of the following statements about patient-controlled analgesia using opioids is true?
(A) It is not associated with respiratory depression
(B) It obviates loading doses
(C) It requires a background opioid infusion to be effective
(D) It requires intravenous administration to be effective
(E) It requires less drug than intramuscular dosing for similar analgesia
Reveal Answer
ADVANCED
Regional & Pain
Which of the following statements concerning neuroleptic malignant syndrome is true?
(A) It does not respond to dantrolene therapy
(B) It is inherited as an autosomal trait
(C) It is not triggered by succinylcholine
(D) It occurs after long-term use of L-dopa
(E) The halothane-caffeine contracture test is negative in susceptible patients
Reveal Answer
ADVANCED
General
Following protamine administration, profound pulmonary hypertension is most likely initiated by release of
(A) epinephrine
(B) histamine
(C) leukotriene
(D) norepinephrine
(E) thromboxane
Reveal Answer
ADVANCED
Pharmacology & Pharmacokinetics
Cardiac
Which of the following statements concerning the management of diabetes mellitus during pregnancy is true?
(A) Insulin requirements remain essentially unchanged during pregnancy
(B) Maternal blood glucose concentration of 200 mg/dL is optimal
(C) Maternal hyperglycemia may cause neonatal acidosis
(D) Neonatal hyperglycemia is common
(E) Infants delivered under general anesthesia have lower Apgar scores than those delivered under spinal anesthesia
Reveal Answer
ADVANCED
OB
A 57-year-old man has back pain, a heart rate of 90 bpm, decreased pulse in the left arm, and blood pressure of 200/110 mmHg. During infusion of nitroprusside, heart rate increases to 115 bpm and blood pressure decreases to 140/80 mmHg. The most appropriate management at this time is administration of
(A) droperidol
(B) nifedipine
(C) normal saline solution
(D) propranolol
(E) verapamil
Reveal Answer
ADVANCED
General
Neostigmine administered intravenously without atropine can produce each of the following EXCEPT
(A) arousal
(B) bradycardia
(C) bronchoconstriction
(D) increased gastric motility
(E) increased urinary bladder tone
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics