Following cardiopulmonary bypass, right ventricular distention is noted after infusion of protamine 40 mg. Pulmonary artery pressure has increased from 25/18 to 50/30 mmHg and systemic arterial pressure has decreased from 110/65 to 0 mmHg. Which of the following is the most appropriate treatment?
(A) Administration of amrinone
(B) Administration of nitroglycerin
(C) Administration of phenylephrine
(D) Initiation of intra-aortic balloon pump assist
(E) Reheparinization and resumption of cardiopulmonary bypass
A 24-year-old woman with abruptio placentae at 38 weeks' gestation has bleeding at the site of the intravenous catheter. Which of the following is the most likely cause?
(A) Diffuse vasculitis
(B) Disseminated intravascular coagulation
(C) Isolated factor VIII deficiency
(D) Primary fibrinolysis
(E) Vitamin K deficiency
B
Compared with adults, neonatal respiratory function is characterized by
(A) a lower ratio of dead space to tidal volume
(B) a more compliant chest wall
(C) a more positive intrapleural pressure at end-expiration
(D) less susceptibility to atelectasis
(E) the same oxygen requirement per kilogram of body weight
A 54-year-old man is scheduled for open reduction of a fracture sustained when he jumped from a burning building. The carboxyhemoglobin concentration is 25%. Which of the following is the most reliable indicator of adequate oxygenation during general anesthesia?
(A) PaO2 of 300 mmHg
(B) pH of 7.38 with a PaCO2 of 41 mmHg
(C) Mixed venous PO2 of 45 mmHg
(D) Oxyhemoglobin saturation of 100% measured by co-oximeter