Anesthesia Hub -

10 Random Questions

Which of the following statements concerning the pharmacokinetics of local anesthetics is true?

(A) Decreased molecular weight is associated with decreased incidence of allergic reactions
(B) Decreased protein binding is associated with decreased systemic toxicity
(C) Increased ionization is associated with increased placental transfer
(D) Increased lipid solubility is associated with faster onset
(E) Presence of an ester linkage is associated with increased duration of action

Compared with the response of a normal patient, administration of a bolus dose of pancuronium (0.15 mg/kg) to a patient with cirrhosis and ascites would be associated with

(A) longer duration
(B) more rapid onset
(C) more intense block
(D) more difficult reversibility
(E) similar pharmacokinetics

BASIC Pharmacology & Pharmacokinetics

Pulmonary artery occlusion pressure

(A) does not reliably reflect left ventricular end-diastolic volume when left ventricular compliance is reduced
(B) inaccurately reflects left atrial pressure when left atrial pressure exceeds 15 mmHg
(C) is measured at end-inspiration in mechanically ventilated patients
(D) overestimates left atrial pressure in patients with poor lung compliance
(E) reflects left atrial pressure only if the catheter tip is located in zone II of the lung

ADVANCED Equipment & Physics General Cardiac

Each of the following changes is expected with deliberate hypothermia EXCEPT

(A) decreased unloading of oxygen from hemoglobin
(B) a 5% decrease in MAC for each 1°C decrease in temperature
(C) increased arterial oxygen and carbon dioxide contents
(D) a 50% decrease in cerebral metabolic rate at 28°C
(E) spike and dome EEG activity at temperatures below 30°C

BASIC General Cardiac

During halothane anesthesia with spontaneous ventilation, the most reliable sign of malignant hyperthermia is

(A) hypertension
(B) increased temperature
(C) increased minute ventilation
(D) muscle rigidity
(E) tachycardia

In a patient taking a beta-adrenergic blocker, the drug most likely to produce atrioventricular junctional block is

(A) diltiazem
(B) fentanyl
(C) halothane
(D) nifedipine
(E) verapamil

BASIC Pharmacology & Pharmacokinetics

A 55-year-old man requires intravenous lidocaine for multifocal premature ventricular contractions occurring in the first hour after a below-knee amputation. He has alcoholic cirrhosis, portal hypertension, and ascites. Which of the following correctly describes the appropriate modification of the usual loading bolus and maintenance infusion of lidocaine?

(A) Larger bolus, faster infusion
(B) Larger bolus, slower infusion
(C) Smaller bolus, faster infusion
(D) Smaller bolus, slower infusion
(E) No change necessary

During postoperative indirect laryngoscopy, the vocal cords appear symmetric during quiet breathing and approximate to the left of midline during phonation. The most likely cause is

(A) pure abductor paralysis of the left cord
(B) pure abductor paralysis of the right cord
(C) abductor and adductor paralysis of the left cord
(D) abductor and adductor paralysis of the right cord
(E) adductor paralysis of both cords

ADVANCED Regional & Pain

During direct intra-arterial measurement of blood pressure

(A) the mean arterial pressure will be unaffected by small air bubbles in the system
(B) an underdamped system will overestimate the mean arterial pressure
(C) an underdamped system will overestimate the diastolic pressure
(D) long tubing from the catheter to the transducer will tend to decrease resonance in the system
(E) calibration of the transducer by opening a stopcock to air at the sternal angle will overestimate the mean

BASIC Equipment & Physics

Which of the following is the most appropriate initial management of a patient with hypotension secondary to sepsis?

(A) Calcium chloride
(B) Corticosteroids
(C) Crystalloid infusion
(D) Dopamine
(E) Fresh frozen plasma

BASIC Respiratory & Critical Care General