A 7-year-old, obese, 30-kg boy was anesthetized using an adult circle system containing a 3-liter bag and mask. Induction with nitrous oxide (2 liters), oxygen (1 liter), and enflurane 3% was characterized by three minutes of hyperventilation followed by apnea. Forty-five seconds later, the child moved and became difficult to control. The most likely cause of the movement is
(A) decreased alveolar concentration of enflurane during the period of apnea
(B) excessive uptake of enflurane by the child's fat
(C) higher fresh gas flows required with use of an adult circle system in a child
A 20-kg, 6-year-old boy is undergoing strabismus surgery under anesthesia with sevoflurane, nitrous oxide, and oxygen. The heart rate suddenly decreases from 85 to 40 bpm. Which of the following is the most appropriate first step in management?
The mortality rate of patients given drug A is 12% (8 of 66) and the mortality rate of patients given drug B is 15% (10 of 66). Which of the following tests is most appropriate to compare these mortality rates?
A 57-year-old man with hepatocellular disease is scheduled to undergo a colectomy for colon cancer. Preoperative laboratory studies show a plasma albumin concentration of 2.4 g/dl (normal = 3.5 to 5.5 g/dl); prothrombin time is 16 sec (control 12 sec). Which of the following statements concerning the anesthetic management of this patient is true?
(A) Atracurium will have a prolonged duration of action
(B) The risk for perioperative hyperglycemia is increased
(C) Mivacurium will have a shortened duration of action
(D) The unbound fraction of thiopental will be increased
(E) Vitamin K injection will normalize the prothrombin time
After the first 70 minutes of a transurethral resection of the prostate, a 70-year-old man becomes confused and has tachycardia, hypertension, and shortness of breath. Serum sodium concentration is 116 mEq/L. After informing the surgeon that the procedure should be terminated as soon as possible, the most appropriate next step would be to
(A) administer furosemide
(B) administer labetalol
(C) administer 3% sodium chloride
(D) change the irrigating solution to normal saline