A 50-year-old man with alcoholism and jaundice is scheduled to undergo umbilical herniorrhaphy. An increase in which of the following best indicates impaired synthetic hepatic function?
Prolonged respiratory depression following administration of morphine is more likely in patients with chronic renal faillure than in patients with normal kidney function because of
Following maternal epidural injection, fetal exposure to chloroprocaine is lower than fetal exposure to bupivacaine for which of the following reasons?
(A) Chloroprocaine is metabolized by plasma cholinesterase
(B) Chloroprocaine is more protein bound
(C) Chloroprocaine is not readily absorbed from the epidural space
(D) The ionized fraction of chloroprocaine in the fetal circulation is smaller
(E) The pKa of chloroprocaine is less than that of bupivacaine
Two months ago a 68-year-old man with insulin-dependent diabetes mellitus had a transurethral resection of the prostate under spinal anesthesia with tetracaine plus epinephrine. He now has numbness and tingling in both feet and disturbance of gait. Physical examination demonstrates stocking-type hypesthesia of both feet and ankles. The most likely diagnosis is
(A) anterior spinal artery syndrome
(B) diabetic neuropathy
(C) adhesive arachnoiditis
(D) cauda equina syndrome
(E) peripheral nerve injury from the lithotomy position