10 Random Questions
The shorter duration of action of alfentanil relative to fentanyl is due to its
(A) greater lipid solubility
(B) increased clearance
(C) increased rate of hepatic metabolism
(D) lesser protein binding
(E) smaller volume of distribution
Reveal Answer
Which of the following statements concerning carbon monoxide poisoning is true?
(A) Diagnosis is excluded if the PaO2 is greater than 300 mmHg while breathing 100% oxygen
(B) Increased inspired oxygen concentration accelerates displacement of carbon monoxide from hemoglobin
(C) Methylene blue decreases binding of carbon monoxide to hemoglobin
(D) Pulse oximetry accurately reflects hemoglobin oxygen saturation
(E) Tissue oxygen delivery is normal
Reveal Answer
ADVANCED
Respiratory & Critical Care
General
Each of the following conditions is associated with autonomic hyperreflexia in patients with spinal cord injury EXCEPT
(A) bradycardia
(B) flushing below the level of injury
(C) headache
(D) sweating above the level of injury
(E) systolic hypertension
Reveal Answer
ADVANCED
General
Compared with similar use in adults, routine use of succinylcholine in children is hazardous because of the increased risk for which of the following?
(A) Anaphylactoid reaction
(B) Phase II blockade
(C) Pseudocholinesterase deficiency
(D) Pulmonary aspiration
(E) Undiagnosed myopathy
Reveal Answer
ADVANCED
Pharmacology & Pharmacokinetics
Pediatric
If a patient with excessive bleeding during exploratory laparotomy has a normal activated clotting time, the LEAST likely cause of the bleeding is
(A) antithrombin III deficiency
(B) dilutional thrombocytopenia
(C) fibrinolysis
(D) administration of heparin 5000 units
(E) preoperative ingestion of aspirin
Reveal Answer
ADVANCED
Cardiac
During induction of anesthesia for cesarean delivery, pancuronium is inadvertently substituted for succinylcholine. The neonate shows no clinical signs of muscle relaxation because pancuronium is
(A) highly ionized
(B) highly protein bound
(C) a large molecule
(D) lipid soluble
(E) unaffected by "ion trapping"
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
When methylmethacrylate is inserted into the femur, each of the following may occur EXCEPT
(A) monomer metabolic breakdown
(B) vasodilation
(C) hypercarbia
(D) hypoxia
(E) increased intramedullary pressure
Reveal Answer
ADVANCED
General
Which of the following is a side effect of beta-adrenergic blockade?
(A) Cerebral vasodilation
(B) Decreased left ventricular filling pressures
(C) Hypokalemia
(D) Increased airway resistance
(E) Uterine relaxation
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
A 26-year-old woman has headache, nausea, and photophobia 36 hours after cesarean delivery for chorioamnionitis using subarachnoid block. Temperature is 38.8°C and leukocyte count is 14,200/mm3. Which of the following is the most appropriate next step in management?
(A) Oral ibuprofen
(B) Intravenous caffeine sodium benzoate
(C) Intravenous hydration
(D) Epidural blood patch
(E) Diagnostic lumbar puncture
Reveal Answer
ADVANCED
OB
A patient develops jaundice one week after undergoing laparoscopic cholecystectomy during halothane anesthesia. Laboratory studies show an increased serum alkaline phosphatase concentration, a mildly increased serum aspartate aminotransferase concentration, and a markedly increased conjugated bilirubin fraction. Which of the following is the most likely diagnosis?
(A) Biliary obstruction
(B) Gilbert's disease
(C) Halothane-associated hepatitis
(D) Hematoma resorption
(E) Infectious hepatitis
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
General