10 Random Questions
The need for increased doses of nondepolarizing muscle relaxants in patients with extensive burns is best explained by
(A) increased protein binding
(B) hypermetabolism
(C) increased glomerular filtration rate
(D) proliferation of receptors on burned muscle
(E) decreased volume of distribution
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
Normal pseudocholinesterase
(A) is highly concentrated at the motor end-plate
(B) hydrolyzes succinylcholine by Hofmann elimination
(C) is produced primarily at nerve terminals
(D) is antagonized by acetylcholinesterase inhibitors
(E) resists dibucaine inhibition more than its atypical variant
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
Which property of oxygen is detected by the fail-safe device on the anesthesia machine?
(A) Concentration
(B) Flow
(C) Pressure
(D) Partial pressure
(E) Reserve volume
Reveal Answer
BASIC
Equipment & Physics
Intraoperatively, the occurrence of prominent "a" waves on the central venous pressure waveform can be explained by each of the following EXCEPT
(A) acute right ventricular failure
(B) atrial flutter
(C) complete heart block
(D) onset of junctional tachycardia
(E) ventricular pacing
Reveal Answer
ADVANCED
Equipment & Physics
Cardiac
Which of the following findings on the left is most likely to be associated with an increased risk of complications with cannulation of the left internal jugular vein compared with cannulation of the right internal jugular vein?
(A) Longer recurrent laryngeal nerve
(B) Lower location of the cupola of the pleura
(C) More acute angle between the internal jugular and innominate veins
(D) More anterior location of the phrenic nerve
(E) Presence of the thoracic duct
Reveal Answer
BASIC
General
Which of the following statements best describes the decrease in cerebral metabolic rate that occurs with administration of volatile anesthetics?
(A) It is independent of anesthetic dose
(B) It is maximal when the EEG is isoelectric
(C) It is more profound with halothane than isoflurane at equipotent doses
(D) It is not affected by enflurane-induced EEG hyperactivity
(E) It parallels changes in cerebral blood flow at mean arterial pressures of 50 to 150 mmHg
Reveal Answer
Following the administration of 4 MAC hours of enflurane, peak serum concentrations of inorganic fluoride are highest in patients who
(A) are physically dependent on barbiturates
(B) are taking isoniazid chronically to suppress tuberculosis
(C) are epileptics taking phenytoin chronically
(D) are obese
(E) consume alcohol regularly
Reveal Answer
Which of the following is associated with the application of a transdermal fentanyl patch?
(A) Achievement of a peak plasma level within one hour
(B) Continued uptake after patch removal
(C) Dose-independent plasma clearance
(D) Tachyphylaxis when used for cancer pain
(E) Naloxone-resistant toxicity
Reveal Answer
ADVANCED
Pharmacology & Pharmacokinetics
Regional & Pain
Which of the following is a known effect of propofol?
(A) Decreased amplitude of somatosensory evoked potentials
(B) Induction of malignant hyperthermia
(C) Inhibition of cytochrome P450
(D) Initiation of porphyria
(E) Suppression of adrenocortical function
Reveal Answer
BASIC
Pharmacology & Pharmacokinetics
A 35-year-old woman with systemic lupus erythematosus is admitted to the critical care unit following sudden onset of severe chest pain. Examination shows tachycardia, hypotension, pulmonary edema, and a blowing systolic murmur in the left parasternal region. The most appropriate management is
(A) aerosol administration of terbutaline
(B) intravenous infusion of phenylephrine and nitroglycerin
(C) intravenous infusion of esmolol
(D) intravenous infusion of epinephrine and nitroprusside
(E) volume loading with lactated Ringer's solution
Reveal Answer
ADVANCED
General