In a healthy 70-kg adult, which of the following is the most likely effect of intravenous administration of morphine 10 mg on ventilatory responses?
(A) Increased response to hypoxia and decreased response to hypercarbia
(B) Decreased response to hypercarbia and no change in response to hypoxia
(C) Decreased response to both hypoxia and hypercarbia
(D) No change in response to hypercarbia and decreased response to hypoxia
(E) No change in response to hypoxia or hypercarbia
C
During induction of anesthesia in a 70-year-old man with aortic stenosis, the blood pressure decreases from 140/ 80 to 70/45 mmHg as the cardiac rhythm changes from normal sinus at 70 bpm to junctional at 120 bpm. The most appropriate initial therapy would be
The cardiovascular effects of an inhalational anesthetic are evaluated in 10 normal volunteers in the awake resting state and after 15 minutes of constant inspired concentration. Results were analyzed by t-test for paired data and are presented below as mean +/- standard deviation. Based on these data, which of the following conclusions is most valid?
(A) A decrease in cardiac output would have been evident if more subjects were included in the study
(B) The anesthetic decreases mean arterial pressure
(C) The anesthetic does not cause cardiac depression
(D) The anesthetic is unsafe for patients with coronary after disease
(E) There is a 95% to 100% chance that the anesthetic increases heart rate
Four and one-half hours after initiation of general anesthesia for a radical hysterectomy, a 65-kg patient has a heart rate of 90 bpm, blood pressure of 100/70 mmHg, pulmonary artery occlusion pressure of 9 mmHg, and cardiac output of 2.8 L/min. Urine output has been 20 ml over the last two hours. The most appropriate next step is
(A) administration of furosemide
(B) administration of indigo carmine
(C) administration of mannitol
(D) bolus infusion of normal saline solution
(E) infusion of dopamine in renal dose
D
Delirium produced by high doses of atropine can be reversed by intravenous injection of
A 75-year-old man is confused, restless, and disoriented two days after an aortic aneurysm repair. Serum sodium concentration is 112 mEq/L, serum osmolality is low, and urine is hypertonic. The most appropriate treatment is
(A) restriction of fluid intake
(B) administration of isotonic saline solution
(C) administration of hypertonic (3%) saline solution