A normal adult is receiving general anesthesia via a standard circle system and controlled ventilation. Mass spectrometer data are shown. Which event is most compatible with these data?
A 157 cm (5 ft 2 in), 180-kg, 40-year-old woman has a PaO2 of 65 mmHg, a PaCO2 of 38 mmHg, and a pH of 7.43 while breathing room air preoperatively. The most likely cause of these values is
(A) decreased hypoxic ventilatory drive
(B) higher than normal oxygen extraction from blood
(C) lower than normal cardiac output
(D) lower than normal functional residual capacity
A 58-year-old man undergoes repeat coronary artery bypass grafting. Which of the following is LEAST likely to decrease the need for exogenous blood transfusion?
(A) Cell saver blood collection before and after cardiopulmonary bypass
(B) Epsilon-aminocaproic acid administered during cardiopulmonary bypass
(C) High-dose aprotinin administered during cardiopulmonary bypass
(D) Tranexamic acid infusion during cardiopulmonary bypass
(E) Desmospressin administered after cardiopulmonary bypass
A 70-kg man with ischemic heart disease is undergoing abdominal aortic aneurysm resection. At the time of infrarenal cross-clamping, 0.2-mV ST-segment depression appears on lead V5 of the ECG. Hemodynamic changes occurring at the same time are shown below. Systemic blood pressure 90/50 --> 150/90; Heart rate 80 --> 95; PAp 20/10 --> 45/24; Mean pulmonary artery occlusion pressure (mmHg) 10 --> 23; Cardiac output (L/min) 4.5 --> 3.2. Ischemia would be decreased by restoring the pre-clamp level of each of the following EXCEPT