Following enflurane anesthesia, serum free fluoride concentration is most likely to be increased in association with long-term use of
A 16-year-old girl is receiving isoflurane, nitrous oxide, oxygen, and pancuronium for insertion of a Harrington rod. In order to perform a "wake-up test" the muscle relaxant was antagonized with neostigmine 2.5 mg and atropine 1 mg. The patient abruptly moved all extremities and was given thiopental 100 mg and succinylcholine 100 mg rapidly. Forty-five minutes later no twitch could be elicited with a nerve stimulator. The most likely explanation is
A 33-year-old woman is scheduled for emergency appendectomy under general anesthesia. She has hypertrophic cardiomyopathy and has had two episodes of syncope in the past year. Which of the following statements concerning anesthetic management is true?
A 32-year-old man is scheduled for hernia repair. He underwent heart transplantation for cardiomyopathy five years ago. Which of the following findings is most likely?
During exploration of the posterior fossa with the patient in the sitting position, blood pressure decreases from 120/70 to 70/40 mmHg, central venous pressure increases from 6 to 16 mmHg, oxygen saturation decreases to 88%, nitrogen is detected by the mass spectrometer, and premature ventricular contractions appear on the ECG. The most appropriate management is to
During induced hypotension for clipping of a cerebral aneurysm in a 20-degree head-up position, the arterial pressure transducer should be zero referenced at which level?
A patient undergoes axillary block for placement of an arteriovenous shunt in the forearm. Blockade of the musculocutaneous nerve is not achieved. Injection of a local anesthetic at which of the following sites will provide the required sensory block?
A 70-kg, 77-year-old man Is undergoing left nephrectomy with nitrous oxide, oxygen, fentanyl, and midazolam anesthesia. He has a 90 pack-year history of cigarette smoking and has chronic obstructive pulmonary disease. One hour after incision, expiratory wheezing occurs and peak Inspiratory pressure increases from 35 to 65 cmH20; end-tidal PCO2 is unchanged, but SpO2 decreases from 97% to 88%. The most likely cause is
Compared with halothane, desflurane has which of the following characteristics?
The metabolism of which of the following hypotensive agents is most likely to be affected in patients with severe renal disease?