Which of the following drugs decreases lower esophageal sphincter tone?
(A) Edrophonium
(B) Glycopyrrolate
(C) Metoclopramide
(D) Prochlorperazine
(E) Succinylcholine
B
Which of the following is most likely to occur during deliberate hypotension with trimethaphan?
(A) Bronchoconstriction
(B) Cerebral vasodilation
(C) Increased heart rate
(D) Potentiation of pancuronium
(E) Pupillary constriction
C
A 27-year-old man with chronic renal failure is to undergo revision of an arteriovenous graft. He insists on general anesthesia. Hemodialysis was completed two hours ago, and serum potassium concentration is now 5 mEq/L. Which of the following statements concerning anesthetic management of this patient is true?
(A) Enflurane is contraindicated
(B) Succinylcholine is contraindicated
(C) Neostigmine will be required in larger than usual dosage
(D) The duration of action of atracurium will be prolonged
(E) The duration of action of propofol will be unchanged
E
A 52-year-old woman undergoes facial surgery during general endotracheal anesthesia. The ventilator is set to deliver a tidal volume of 600 ml and a respiratory rate of 10/min at an FiO2 of 1.0. SpO2 is 100%, peak inspiratory pressure is 18 cmH2O, and PetCO2 is 40 mmHg. The surgeon flexes the patient's head so the chin touches the chest. Which of the following findings indicates that endobronchial intubation has NOT occurred?
(A) Fluctuating capnographic waveform
(B) Greater expiratory volume than inspiratory volume
The plasma concentration of an intravenously administered drug follows the two-compartment kinetic model shown in the graph. Which of the following events is illustrated by the decline in plasma concentration shown at Time #2?
(A) Decreasing activity of the drug at its receptor site
(B) Distribution from plasma to tissue
(C) Elimination of the drug from plasma
(D) Increasing volume of distribution
(E) Redistribution from vessel-rich groups to vessel-poor groups
C
A 65-year-old woman has respiratory distress and loss of consciousness immediately following superficial and deep cervical plexus block for right carotid endarterectomy. Which of the following is the most likely cause?
During a right lower lobe resection, SpO2 decreases from 99% to 70% after institution of one-lung ventilation. FiO2 is 1.0. The most appropriate management is to
(A) administer an inhaled bronchodilator
(B) apply continuous positive airway pressure to the right lung
(C) apply positive end-expiratory pressure to the left lung
Failure to block the musculocutaneous nerve adequately during the axillary approach to brachial plexus block will result in inadequate anesthesia of the