A 2600-g neonate is to undergo surgical repair of a small gastroschisis. The infant is preoxygenated with 100% oxygen. Arterial hemoglobin desaturation is noted during laryngoscopy after a rapid-sequence induction. Which of the following is the most likely cause?
(A) High fetal hemoglobin concentration
(B) High ratio of oxygen consumption to functional residual capacity
(C) Low functional residual capacity in milliliters per kilogram
A 26-year-old woman has weakness on extension of the right knee one day after uneventful vaginal delivery under spinal anesthesia with lidocaine. The most likely cause is
(A) femoral nerve injury from thigh abduction
(B) obturator nerve injury from obstetric forceps
(C) peroneal nerve compression from the leg support
(D) saphenous nerve injury from the stirrups
(E) chemical arachnoiditis following the spinal anesthetic
A
Which of the following statements concerning cerebral blood flow (CBF) during anesthesia is true?
(A) CBF changes minimally when PaC02 increases from 30 to 40 mmHg
(B) CBF changes minimally when P02 decreases from 160 to 100 mmHg
(C) CBF is autoregulated when mean arterial pressure is 40 mmHg
(D) CBF is coupled to cerebral metabolism during isoflurane anesthesia
(E) CBF is unaffected by 1.2% isoflurane at a PaC02 of 40 mmHg
B
The flow-volume loop indicated by the "X" is characteristic of
You are asked to evaluate a 2000-g male infant three hours after vaginal delivery because of a respiratory rate of 50/min, pulse rate of 115 bpm, and the following arterial blood gas values while breathing room air: PaO2 64 mmHg, PaCO2 43 mmHg, and pH 7.33. His mother received meperidine 75 mg two hours before delivery. Appropriate management includes
(A) administration of naloxone 50 mcg intramuscularly
(B) increasing the FiO2 to 0.4
(C) intubation and mechanical ventilation at an FiO2 of 0.5
(D) administration of oxygen 50% with 5 cm H2O continuous positive airway pressure
In an anesthetized patient being mechanically ventilated, end-expired carbon dioxide is 58 mmHg and peak inspiratory airway pressure is 15 cmH20. Ventilator settings indicate a delivered tidal volume of 800 ml, but the expiratory flowmeter shows a tidal volume of 360 ml. Which of the following is the most likely cause of this discrepancy?
(A) Fresh gas flow of 0.5 L/min
(B) Incompetence of the pressure-relief valve
(C) Low ventilatory rate
(D) Presence of a hole in the ventilator bellows
(E) Prolongation of the inspiratory phase
B
A patient has tonic movements of the head and neck, nystagmus, and slurred speech after receiving metoclopramide for nausea after nitrous oxide-opioid anesthesia. The most appropriate pharmacologic treatment is