10 Random Questions


A patient with jaundice who has a minimally elevated SGOT (AST), markedly elevated alkaline phosphatase, and normal prothrombin time is to receive a muscle relaxant. Which of the following is most likely in this patient?

BASIC Pharmacology & Pharmacokinetics

A normotensive 66-year-old man undergoes total hip arthroplasty. Mean arterial pressure is maintained at 60 mmHg with isoflurane and labetalol; intraoperative FiO2 is 1.0. Eight units of red blood cells are administered intraoperatively because of an injury to the femoral artery. Five days later, the patient develops jaundice. Which of the following is the most likely cause of the jaundice?

BASIC Transfusions & Fluids

A 75-year-old man with a left bundle branch block is undergoing placement of a pulmonary artery catheter through the right internal jugular vein. He becomes pale and his heart rate decreases to 40 bpm when the catheter tip enters the right ventricle. The most likely cause is

ADVANCED Equipment & Physics Cardiac

Which of the following is most responsible for the duration of action of local anesthetics?

BASIC Pharmacology & Pharmacokinetics Regional & Pain

Compared with epidural administration of hydrophilic opioids, epidural administration of lipophilic opioids is associated with

ADVANCED Pharmacology & Pharmacokinetics Regional & Pain

A 64-year-old, 70-kg woman treated with lithium for manic-depressive psychosis is given methohexital 90 mg and succinylcholine 35 mg intravenously for electroconvulsive therapy. Ten minutes later she remains sedated and the peripheral nerve stimulator shows a decreased twitch response. The most likely explanation is

ADVANCED Pharmacology & Pharmacokinetics

Which of the following nerves should be blocked for an operation at the medial aspect of the lower leg?


Ketamine decreases

BASIC Pharmacology & Pharmacokinetics

The decrease in hematocrit that accompanies acute major blood loss results from


Which of the following pulmonary components is altered the most in a morbidly obese patient?

BASIC Respiratory & Critical Care